Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 169037-23-4, name is 5-(Trifluoromethoxy)indoline-2,3-dione, A new synthetic method of this compound is introduced below., HPLC of Formula: C9H4F3NO3
3beta-hydroxy-5alpha,8alpha-peroxyandrost-6-ene-17-hydrazine obtained in the step (f)(100 mg, 0.30 mmol) and 5-trifluoromethoxy-isatin (76.2 mg, 0.30 mmol) dissolved in 20 mLIn absolute ethanol, placed in a 50 mL single-necked flask, and the system was heated to 50 C for 2 to 4 hours.The reaction was terminated until no starting material was reacted. Decomposition under reduced pressure, purification by silica gel column,The product was obtained as a pale yellow solid, 114.2 mg, yield: 70%.
The synthetic route of 169037-23-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Qiqihar Medical University; Bu Ming; Wang Haijun; Wang Jing; Lin Yu; Li Hongling; Ma Yukun; (18 pag.)CN108707180; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem