Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 52351-75-4, name is 6-Methoxyindoline-2,3-dione, This compound has unique chemical properties. The synthetic route is as follows., category: indolines-derivatives
(c) Methyl 4-methoxy-anthranilate One hundred fifty-eight grams (0.89 mol) of 6-methoxy-isatine are suspended in 1300 ml of methanol and mixed with a solution of 54 gm (1.34 mol) of sodium ethoxide in 500 ml of methanol. One hundred eight milliliters (1.07 mol) of 30% hydrogen peroxide are added thereto dropwise, under stirring, and the resulting mixture is stirred for 30 minutes. The contents of the flask are concentrated down to half their volume, mixed with water, and adjusted to a pH of 5 to 6 with glacial acetic acid. After extraction with methylene chloride, the mixture is subjected to suction filtration, kieselguhr being used, and dried with sodium sulfate, and the solvent is distilled off. The residue is recrystallized from petroleum ether/cyclohexane (2:1). M.p: 80-82 C., Yield: 109 gm (67.7% of theory). The following compounds are prepared by analogous procedures:
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 52351-75-4.
Reference:
Patent; Dr. Karl Thomae GmbH; US4518597; (1985); A;,
Indoline – Wikipedia,
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