Application of 5394-18-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5394-18-3, name is 2-(4-Bromobutyl)isoindoline-1,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Example 26; Compound of Formula VII, Wherein R1 and R2 Taken Together with the Carbon Atom to which they are Attached are CCH2, and R20=(4-Pyridin-3-yl-1H-triazol-1-ylbutyl), Rx=Ac; Step 26a.; To a solution of commercially available 2-(4-bromo-butyl)-isoindole-1,3-dione (7.1 mmol) in DMF (7 ml) was added sodium azide (5 eq.). After stirring at room temperature overnight, the mixture was diluted with water and extracted with EtOAc. The combined organic extracts were washed 3 times with water, once with brine, dried over MgSO4, filtered and concentrated under vacuum to give the desired azide product in quantitative yield. 13C NMR (CDCl3, ppm) delta: 168.4, 134.0, 132.1, 123.3, 50.9, 37.3, 26.3, 26.3, 25.9.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(4-Bromobutyl)isoindoline-1,3-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Or, Yat Sun; Tang, Datong; Gai, Yonghua; Sun, Ying; Xu, Guoyou; Wang, Zhe; US2006/122128; (2006); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem