In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 24566-80-1, name is 2-(10-Bromodecyl)isoindoline-1,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below. Application In Synthesis of 2-(10-Bromodecyl)isoindoline-1,3-dione
A suspension of 2-(10-bromodecyl)isoindoline-1,3-dione (190-1) (366 mg, 1 mmol) and thiourea (190-2) (76.1 mg, 1 mmol) in EtOH (1 mL) were heated to 70 C in a glass vial under nitrogen for 3 hours. The solvent was removed and the white solid triturated with ether, filtered, and washed with additional ether to give 2-(10-(1,3-dioxoisoindolin-2-yl)decyl)isothiouronium bromide (190-3) (235 mg, 0.5311 mmol, 53.1 %) as a white powder. LC/MS (ES+): m/z 326.8 [M + H]+
The synthetic route of 24566-80-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; C4 THERAPEUTICS, INC.; PHILLIPS, Andrew, J.; NASVESCHUK, Chris, G.; HENDERSON, James, A.; LIANG, Yanke; FITZGERALD, Mark, E.; MICHAEL, Ryan, E.; (790 pag.)WO2017/197056; (2017); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem