Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 99365-40-9, name is 6-Bromoindolin-2-one, A new synthetic method of this compound is introduced below., Recommanded Product: 6-Bromoindolin-2-one
4 mmol of 6-bromo-2-indolone (XI) was dissolved in 20 ml of tetrahydrofuran solution, 4.8 m mol of sodium hydrogencarbonate was added, and then 8 mmol of di-tert-butyl dicarbonate was added, and the reaction system was stirred at 66 C. The reaction was quenched with TLC until the title material was evaporated. The mixture was evaporated to ethyl ether. Separation and purification with n-hexane:ethyl acetate = 5:1 as eluent gave 668 mg of white solid.The yield was 54%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; UNIV GUANGDONG TECHNOLOGY; Guangdong University of Technology; ZHUANG GUISHENG; Zhuang Guisheng; LIU YAN; Liu Yan; LU HANBIN; Lu Hanbin; HE HONGYUN; He Hongyun; MARUOKA HIROJI; Wan Gangqier; (32 pag.)CN108299491; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem