Adding a certain compound to certain chemical reactions, such as: 3891-07-4, name is 2-(2-Hydroxyethyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3891-07-4, category: indolines-derivatives
To a solution of N-(2-hydroxyethyl)phthalimide (2g, 10.5mmol) in anhydrous tetrahydrofuran (30mL) was added 60% NaH (0.84 g, 21 mmol) at -5C. The mixture was stirred at the same temperature for 20 min. Commercially available 4b (1.5 mL, 12.6 mmol) was added to the mixture and was stirred at the same temperature for 30 min and then stirred at room temperature for 4 h and filtered. The filtrate was concentrated under reduced pressure to give 5b (2.65 g, 90%) as a off-white solid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(2-Hydroxyethyl)isoindoline-1,3-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Wang, Minghua; Ye, Cheng; Liu, Mingliang; Wu, Zhaoyang; Li, Linhu; Wang, Chunlan; Liu, Xiujun; Guo, Huiyuan; Bioorganic and Medicinal Chemistry Letters; vol. 25; 14; (2015); p. 2782 – 2787;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem