Share a compound : C8H3ClFNO2

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 84378-94-9, name is 4-Chloro-5-fluoroindoline-2,3-dione, A new synthetic method of this compound is introduced below., Application In Synthesis of 4-Chloro-5-fluoroindoline-2,3-dione

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 84378-94-9, name is 4-Chloro-5-fluoroindoline-2,3-dione, A new synthetic method of this compound is introduced below., Application In Synthesis of 4-Chloro-5-fluoroindoline-2,3-dione

General procedure: To an ethanolic solution of triazole-hydrazide 5 (1.0mmol) was added equimolar amount of substituted Isatin (8a-i) and refluxed overnight at 80C. After completion of the reaction, crude obtained was filtered, washed with water to get Isatin-triazole hydrazones (9a-i) which was purified by column chromatography eluted with acetone: DCM (1:9) to afford the title compounds in moderate to good yield [53].

The synthetic route of 84378-94-9 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Aneja, Babita; Khan, Nashrah Sharif; Khan, Parvez; Queen, Aarfa; Hussain, Afzal; Rehman, Md. Tabish; Alajmi, Mohamed F.; El-Seedi, Hesham R.; Ali, Sher; Hassan, Md. Imtaiyaz; Abid, Mohammad; European Journal of Medicinal Chemistry; vol. 163; (2019); p. 840 – 852;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem