Related Products of 6872-06-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 6872-06-6, name is 2-Methylindoline belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
General procedure: N-heterocycle substrate (0.2 mmol), Na-AMO (20 mg, 10 mol%), catechol Q-2 (3.3 mg, 0.02 mmol) was added into a reaction tube. The reaction tube was filled and protected with oxygen using a O2 balloon, then H2O was added into the reaction tube with a syringe. The reaction was allowed to react at room temperature for 20 h. After completion of reaction, the resulting mixture was filtered, washed with EtOAc and extracted by EtOAc. The organic phases were combined, washed with brine and dried with Na2SO4. Next, organic solution was concentrated under reduced vacuum to give the crude product. Finally, the product was purified by silica gel chromatography to yield the pure product.
The synthetic route of 2-Methylindoline has been constantly updated, and we look forward to future research findings.
Reference:
Article; Tang, Tao; Bi, Xiuru; Meng, Xu; Chen, Gexin; Gou, Mingxia; Liu, Xiang; Zhao, Peiqing; Tetrahedron Letters; vol. 61; 5; (2020);,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem