Related Products of 41663-84-7, These common heterocyclic compound, 41663-84-7, name is 2-Methyl-5-nitroisoindoline-1,3-dione, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 6 To a reaction vessel were added 4-nitro-N-methylphthalimide (0.51 g, 0.00248 mol), sodium hydrogen sulfide (0.07 g, 0.00125 mol), biphenyl (0.204 g, 0.00132 mol), triethylamine (0.2 ml, 0.0014 mol), tetrabutylphosphonium bromide (0.15 g, 0.00044 mol) and dry toluene (40 ml). The reaction mixture was allowed to proceed at reflux (approximately 145 C.) for 18 hours. The reaction mixture was sampled and tested by HPLC which indicated a yield of 4,4′-bis(N-methylphthalimide)sulfide of 10% (0.04 g).
Statistics shows that 2-Methyl-5-nitroisoindoline-1,3-dione is playing an increasingly important role. we look forward to future research findings about 41663-84-7.
Reference:
Patent; General Electric Company; US4625037; (1986); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem