Adding a certain compound to certain chemical reactions, such as: 3339-73-9, name is 3-(1,3-Dioxoisoindolin-2-yl)propanoic acid, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3339-73-9, Computed Properties of C11H9NO4
Step 7: To a solution of 137g (20.0 g, 91 mmol) in DCM (250 mL) were added oxalyl chloride (13.8 g, 109 mmol) and DMF (0.1 mL). See Figure 2. The mixture was stirred at RT for 4h. Upon reaction completion, the mixture was concentrated to give 3-(l,3-dioxoisoindolin-2- yl)propanoyl chloride 137h (20.0 g, 92%) as a white solid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-(1,3-Dioxoisoindolin-2-yl)propanoic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; GENENTECH, INC.; CRAWFORD, James John; LEE, Wendy; YOUNG, Wendy B.; WO2015/949; (2015); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem