In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 611-09-6, name is 5-Nitroindoline-2,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below. Application In Synthesis of 5-Nitroindoline-2,3-dione
General procedure: To a magnetically stirred mixture of isatins (1 mmol) and IL I (12.6 mg, 0.05 mmol) were added alkyl-malonates (1 mmol) or 1,3-dicarbonyl compounds (1 mmol) and then the reaction mixture was stirred at room temperature . After completion of the reaction (monitored by TLC), EtOAc was added to the reaction mixture, and [TBD][TFA] was removed by filtration and washed with EtOAc (2 5 ml).The filtrate was evaporated under reduced pressure to give the solid product as a residue in almost pure form. If necessary, the product could further be purified byrecrystallization from ethanol.
The synthetic route of 611-09-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Baghbanian, Seyed Meysam; Tajbakhsh, Mahmood; Farhang, Maryam; Comptes Rendus Chimie; vol. 17; 12; (2014); p. 1160 – 1164;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem