Related Products of 6341-92-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 6341-92-0 as follows.
Is added to the reactor 153.8 mg (0.85 mmol) 6 – chloro – isatin and 102.1 mg (1.02 mmol) 2, 4 – pentanedionato, add 50 ml toluene and 5 ml DMF as the reaction solvent, adding 13.6 mg KMnO4, 7.5 Mg MnO2And 20 mg of strongly acidic ion resin D001 as catalyst, electric jacket is heated to 115 C, magnetic stirring reflux reaction for 9 hours. Thin-layer chromatographic trace to after the reaction is complete, evaporating the solvent under reduced pressure, the filter cake is toluene washing, drying to obtain the target compound 127.2 mg, total yield 56.9%.
According to the analysis of related databases, 6341-92-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shaanxi University of Science and Technology; Liang Chengyuan; Tian Danni; Jia Minyi; Wang Xuechuan; Dong Hao; Wang Qiang; (12 pag.)CN108558895; (2018); A;,
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