Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 7477-63-6, name is 7-Chloroisatin, A new synthetic method of this compound is introduced below., Application In Synthesis of 7-Chloroisatin
General procedure: To a well-stirred solution of aldehyde 1 or isatin 4 (2 mmol) and tetronic acid 2(4 mmol) in ethanol (5 mL) was added sulfamic acid (20 mol percent) with continuous stirring. With the progress of the reaction, a yellowish solid separated out. Upon completion of the reaction (TLC), the resultant solid was filtered, washed with ethanol and dried. The resultant bis-tetronic acid 3/5 was found to be pure and did not require any further purification.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Pandit, Kapil S.; Desai, Uday V.; Wadgaonkar, Prakash P.; Kodam, Kisan M.; Research on Chemical Intermediates; vol. 43; 1; (2017); p. 141 – 152;,
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