Simple exploration of 774-47-0

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 774-47-0, name is 5,6-Difluoroindoline-2,3-dione, A new synthetic method of this compound is introduced below., Application In Synthesis of 5,6-Difluoroindoline-2,3-dione

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 774-47-0, name is 5,6-Difluoroindoline-2,3-dione, A new synthetic method of this compound is introduced below., Application In Synthesis of 5,6-Difluoroindoline-2,3-dione

The 5,6-difluoro isatin(1.83g, 10mmol)Add 10 mL of acetonitrile to a 100 mL round bottom flask.N-methylpiperazine (1.10 g, 11 mmol) was added dropwise, followed by stirring at room temperature for 4 h. After the reaction was monitored by TLC, purification by column chromatography gave a red solid with a yield of 48%.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Sun Yat-sen University; Huang Zhishu; Tan Jiaheng; Che Tong; (27 pag.)CN107540662; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem