Application of 88150-75-8, The chemical industry reduces the impact on the environment during synthesis 88150-75-8, name is Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate, I believe this compound will play a more active role in future production and life.
Orthochlorobenzaldehyde (67.5 g, 0.48 M) was reacted with ethyl 4[2-(phthalimido)ethoxy acetoacetate (100 g, 0.31 M) in the presence of pyridine acetic acid in benzene at 80/82 C. for 12 hrs and cooled to room temperature. To the reaction mass water was added. Organic layer was separated and benzene was distilled out and the residue was washed with hexane.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Purohit, Arun Kumar; Desai, Brahmader Chilu; Shete, Balasaheb Dashrath; Bagwan, Salim Abbas; US2004/44218; (2004); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem