Adding a certain compound to certain chemical reactions, such as: 52537-00-5, name is 6-Chloro-2,3-dihydro-1H-indole, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 52537-00-5, Quality Control of 6-Chloro-2,3-dihydro-1H-indole
EXAMPLE 40 Preparation of 1-Chloro-4,5,8,9,10,11-hexahydro-7H-azepino[4,5-b]pyrrolo[3,2,1-hi]indole Maleic Acid Following the general procedure outlined in EXAMPLE 14, and making non-critical variations but starting with 6-chloro-indoline, the title compound was obtained (amorphous solid). 1H NMR (CD3OD) 6.91, 6.81, 6.77, 4.90, 3.69, 3.34, 3.21; MS (ESI+) for C14H15ClN2 m/z 247.2 (M+H)+.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 6-Chloro-2,3-dihydro-1H-indole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Pharmacia & Upjohn Company; US6407092; (2002); B1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem