Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1336963-95-1, name is 6-Bromo-7-fluoroindoline-2,3-dione, A new synthetic method of this compound is introduced below., Product Details of 1336963-95-1
To a solution of 6-bromo-7-fluoroindoline-2,3-dione (1.41 g, 5.80 mmol) in 2 N NaOH (15 mL) was added H202 (30%, 3 mL) at 0C, the mixture was stirred at 0C for 30 mm. After stirring at rt for 16 h, the mixture was poured into ice water, the solution was acidified with Conc. HC1, the precipitate was filtered and dried in the air to afford the desired product as a white solid (1.2 g, 89% yield)
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; ARAXES PHARMA LLC; LI, Liansheng; FENG, Jun; LONG, Yun Oliver; LIU, Yuan; WU, Tao; REN, Pingda; LIU, Yi; (246 pag.)WO2017/87528; (2017); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem