Electric Literature of 3676-85-5, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 3676-85-5 as follows.
Inthe above reaction scheme, the compound6and 7 was synthesized by literature procedure[2]. To a boiling ethanol solution (10 mL) of 7 (0.2 mmol, 30 mg) was added hydrazinehydrate 50% (0.2 mmol, 1 mL). Thereaction mixture was refluxed at 80 oC for 45 min. After completionof the reaction the reaction mixture was cooled in ice water bath, theprecipitate was collected and dried in room temperature. (Color: yellow solid;Yield: 25 mg (74%)). 1H-NMR spectrum of 8(DMSO-d6, 300MHz, ppm): delta 5.73 (s, 2H), 6.53 (s, 1H), 6.56 (s,1H), 7.30 (d, J = 8.4 Hz, 2H), 7.80 (s, 1H); 13C-NMRspectrum of 8 (DMSO-d6, 75MHz, ppm): delta 157.6, 154.3, 152.9, 128.8, 117.2, 119.3, 116.5, 106.0. 1 H-NMR spectrum of 7 (DMSO-d6,300 MHz, ppm): delta 5.54, (s 2H), 6.83 (dd, J = 6.1 Hz, 1H), 6.9 (d, J = 2.1 Hz, 1H), 7.48 (d, J = 8.4Hz, 1H), 7.58 (s, 1H), 10.24 (s, 1H).FTIR spectrum of 6, 7and8, FTIR (ATR)(nu,cm-1): 3317 (N-H), 1695 (C=O), 1543,1340 (N-O), 1070, 1301 (C-O), 715 (C-H); 3440 (N-H), 1710 (C=O), 1381, 1072 (C-O),746 (C-H) and 3740 (N-H), 1640 (C=O), 1407, 1072 (C-O), 719 (C-H),respectively. UV-Visible absorption of8(c 0.564¡Á10-4 mol/ L, C2H5OH); UV (C2H5OH)lambdamax(log epsilon) 273 (1.949).
According to the analysis of related databases, 3676-85-5, the application of this compound in the production field has become more and more popular.
Reference:
Article; Daniel Thangadurai; Nithya; Rakkiyanasamy; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 211; (2019); p. 132 – 140;,
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