Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 162100-55-2, name is 5-(Trifluoromethyl)indoline, A new synthetic method of this compound is introduced below., name: 5-(Trifluoromethyl)indoline
Example 22 5-Trifluoromethyl-1-(3-pyridylcarbamoyl)indoline (E22) The title compound was prepared as in the method of (Example 2) from 3-pyridylisocyanate and 5-trifluoromethylindoline (D43) to give (E22) (0.12 g, 38%) m.p. 188-189 C. NMR (DMSO-d6) delta: 3.28 (2H, t, J=8), 4.22 (2H, t, J=8), 7.31-7.37 (1H, m), 7.47-7.57 (2H, m), 7.95-8.03 (2H, m), 8.24 (1H, d, J=6), 8.75 (1H, s), 8.90 (1H, s). MH+ 308 C15 H12 N3 OF3 H+ requires 308
The synthetic route of 162100-55-2 has been constantly updated, and we look forward to future research findings.