1504-06-9, name is 3-Methyloxindole, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 3-Methyloxindole
A solution of 3-methylindolin-2-one (50.0 g, 340 mmol) in MeCN (500 mL) was charged with NBS (66.0 g, 374 mmol) portionwise over 30 min at -20 . The resulting reaction mixture was stirred for 30 min, then poured into ice (2 L) and extracted with EtOAc (3×1 L) . The combined organic layers were dried (Na2SO4) and concentrated to afford 5-bromo-3-methylindolin-2-one.1H NMR (300 MHz, CDCl3) delta 8.78 (s, 1 H) , 7.36-7.32 (m, 2 H) , 6.79 (d, J 8.7 Hz, 1 H) , 3.51-3.43 (m, 1 H) , 1.49 (d, J 7.8 Hz, 3 H) .
The synthetic route of 1504-06-9 has been constantly updated, and we look forward to future research findings.