Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20870-78-4, name is 5-Bromoindolin-2-one, This compound has unique chemical properties. The synthetic route is as follows., name: 5-Bromoindolin-2-one
4 mmol of 5-bromo-2-fluorenone (IX) was dissolved in 20 ml of tetrahydrofuran solution, 4.8 mmol of sodium hydrogencarbonate was added, and then 8 mmol of di-tert-butyl dicarbonate was added, and the reaction system was stirred at 66 C. The reaction was quenched by TLC until the material disappeared, and then the mixture was evaporated to ethyl ether.Hexane:Separation and purification of ethyl acetate = 5:1 as eluent gave 670 mg of white solid. The yield was 54%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 20870-78-4.