Adding a certain compound to certain chemical reactions, such as: 7699-18-5, name is 5-Methoxyindolin-2-one, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 7699-18-5, category: indolines-derivatives
General procedure: 4.4.22 (Z)-5-methoxy-3-((2-(thiophen-2-yl)-1H-benzo[d]imidazol-6-yl)methylene)indolin-2-one (6b) Compound 6b was prepared according to the method described for compound 5a, employing aldehyde 14 (114 mg, 0.5 mmol) and 5-methoxyindolin-2-one (12b, 81 mg, 0.5 mmol) to obtain the pure product 6b as a yellow solid (104 mg, 56%); mp: 189-191 C; IR (KBr): 3420, 3152, 2920, 2330, 1689, 1640, 1603, 1476, 1430, 1308, 1209, 1092, 1037, 862 cm-1; 1H NMR (300 MHz, DMSO-d6): delta 10.33 (bs, 1H), 7.94-7.83 (m, 2H), 7.75 (s, 1H), 7.68 (s, 1H), 7.67 (s, 1H), 7.55 (d, J = 8.3 Hz, 1H), 7.34 (d, J = 8.4 Hz, 1H), 7.20 (t, J = 4.9 Hz, 1H), 6.84-6.64 (m, 2H), 3.62 (s, 3H); 13C NMR (75 MHz, CDCl3 + DMSO-d6): delta 168.8, 153.7, 148.6, 137.2, 136.3, 133.0, 128.8, 127.0, 126.3, 124.0, 121.9, 114.1, 113.6, 109.9, 109.4, 108.6, 55.0; MS (ESI): m/z 374 [M + H]+; HRMS (ESI): calcd for C21H16O2N3S m/z 374.09561 [M + H]+; found 374.09577.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methoxyindolin-2-one, other downstream synthetic routes, hurry up and to see.