Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 611-09-6, name is 5-Nitroindoline-2,3-dione, A new synthetic method of this compound is introduced below., Computed Properties of C8H4N2O4
General procedure: A mixture of isatin (1 mmol), reactive methylene compound(1 mmol) and 1,3-dicarbonyl compound (1 mmol)in the presence of [Sipim]Cl (0.05 g) in water (5 mL)was refluxed with stirring in an oil bath. The progress ofthe reaction was monitored by TLC. After completion ofthe reaction, the mixture was filtered and remaining waswashed with warm ethanol (3 × 10 mL) in order to separate[Sipim]Cl catalyst. After cooling the ethanol phase, theprecipitates were filtered. The crude products were purifiedby recrystallization from ethanol (95 %).
The synthetic route of 611-09-6 has been constantly updated, and we look forward to future research findings.