Adding a certain compound to certain chemical reactions, such as: 446292-08-6, name is (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 446292-08-6, Product Details of 446292-08-6
Put the compound of formula II (42.1g), ethanol (252mL), and n-butylamine (47.2g, 8eq) into the reaction flask, warm the temperature to 75-80 C, and hold the reaction for 8-12 hours. After the reaction is completed, cool the reaction solution to 0 to 5 C, heat and stir for 1 hour, filter the obtained solid,The filter cake was rinsed with ethanol (20 mL) and dried to obtain the intermediate compound of formula I (23.3 g), purity (HPLC) 99.57%, and yield 80%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione, and friends who are interested can also refer to it.