Electric Literature of 446292-08-6,Some common heterocyclic compound, 446292-08-6, name is (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione, molecular formula is C22H19N3O6, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
4.45 g (10.6 mmol) of the structural compound of formula (II) was suspended in 100 ml of ethanol, 40 ml of a methylamine aqueous solution (10.2 ml, 142 mmol) was added, reflux for 2 hours, concentrate to dryness under reduced pressure. Add 100 ml of ethanol, continue to concentrate under reduced pressure to dry. The residue was cooled to room temperature, adding 90 ml of methylene chloride, and the mixture was stirred to obtain a dichloromethane solution of the compound of the formula (R-1) go directly to the next step.
The synthetic route of 446292-08-6 has been constantly updated, and we look forward to future research findings.