Reference of 18711-15-4, A common heterocyclic compound, 18711-15-4, name is 4,6-Dichloroisatin, molecular formula is C8H3Cl2NO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Example 15; Process for producing =l, 6-dichlot(at)o-3-(at)(at)5, 6-dimethyl-7-(3-morpholine–l yl- propyl)-7H pyrrolo-(at)2,3-dJpyrimidine-(at) ylJ-hydrazonoJ-1,3-dihyd(at)o-indole-2-on. 108 mg (0.5 millimole) of 4,6-dichloro-isatin was added to 152.2 mg (0.5 millimole) of [5,6-dimethyl-7-(3-morpholine-4-yl-propyl)-7H-pyrrolo[2,3- d]pyrimidine-4-yl]-hydrazine (Example 11) and the mixture was refluxed in 4 ml of ethanol. The precipitated orange yellow crystals were filtered then washed with ethanol and hexane (102 mg; 40 %).
The synthetic route of 18711-15-4 has been constantly updated, and we look forward to future research findings.