Synthetic Route of 2058-72-2, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2058-72-2 as follows.
Weigh accurately 0.2401g 5-bromo-N- methyl isatin,0.0981 g of 1,3-cyclopentadione,0.1621 g of 4-hydroxycoumarin and 0.0508 g of I2 were dissolved in 4 mL of CH2Cl2,After magnetic stirring at 60 C for 24 h,TLC detection,Confirm the reaction has ended,The solvent was removed by rotary evaporation,Column chromatography was used to obtain white solid Ic,Yield 79%
According to the analysis of related databases, 2058-72-2, the application of this compound in the production field has become more and more popular.