Application of 1677-48-1, These common heterocyclic compound, 1677-48-1, name is 5,6-Dichloroindoline-2,3-dione, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
5,6-Dichloro-7-nitroisatin (13i) was obtained in 51% yield from 5,6-dichloroisatin (13g) by using a similar procedure as that for 13h. Mp 200-201 C.; IR: 1784, 1759, 1743, 1626, 1547, 1442, 1332 cm-1; 1 H NMR delta 11.934 (s, 1H), 8.125 (s, 1H); HRMS Calcd for C8 H2 Cl2 N2 O4: 259.9391; Found: 259.9384.
The synthetic route of 1677-48-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; State of Oregon, Acting by and through the Oregon State Board of Higher Education, Acting for and on Behalf of the Oregon Health Sciences University and the University of Oregon; Acea Pharmaceuticals, Inc.; The Regents of the University of California; US5597922; (1997); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem