Share a compound : 6-Bromo-7-fluoroindoline-2,3-dione

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1336963-95-1.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1336963-95-1, name is 6-Bromo-7-fluoroindoline-2,3-dione, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C8H3BrFNO2

H202 (10.0 mL, 98 mmol) was added to a solution of 6-bromo-7-fluoroindoline-2,3-dione (5.4 g, 22.13 mmol) and sodium hydroxide (27.7 mL, 55.3 mmol) in water (20 mL) at 0 C and the reaction mixture was stirred at 0 C for 2 hr. The reaction mixture was acidified by 2N HCI until the pH = 6. The solid was collected by filtration and dried in vacuo to give 2-amino-4-bromo-3-fluorobenzoic acid (4.8 g, 20.51 mmol, 93 % yield) as a yellow solid. LCMS: [M+H] 234.1 .

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1336963-95-1.

Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; JIN, Qi; POHLHAUS, Denise Teotico; SPLETSTOSER, Jared; (320 pag.)WO2017/98440; (2017); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem