Related Products of 59-48-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 59-48-3, Name is Indolin-2-one, SMILES is O=C1NC2=C(C=CC=C2)C1, belongs to indolines-derivatives compound. In a article, author is Liu, Dan, introduce new discover of the category.
Convergent Synthesis of Triindanone-Fused Spiro[bicyclo[2.2.2]octane-2,3 ‘-indolines] via Domino Reaction of 1,3-Indanedione and 3-Methyleneoxindoles
A triethylamine-promoted domino reaction of three molecular 1,3-indanediones with various 3-methyleneoxindoles in refluxing ethanol has been developed. Series of novel polycyclic triindanone-fused spiro[bicyclo[2.2.2]octane-2,3’-indoline] derivatives were successfully synthesized in satisfactory yields with high diastereoselectivity. This domino reaction was accomplished with in situ generation of active cyclic dienes by base-promoted cyclotrimerization or cyclotetramerization of 1,3-indanediones and sequential Diels-Alder reaction of active cyclic dienes with dienophilic 3-methyleneoxindoles.
Related Products of 59-48-3, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 59-48-3.