Synthetic Route of 59-48-3, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 59-48-3, Name is Indolin-2-one, SMILES is O=C1NC2=C(C=CC=C2)C1, belongs to indolines-derivatives compound. In a article, author is Ohshiro, Taichi, introduce new discover of the category.
Voluhemins, new inhibitors of sterolO-acyltransferase, produced byVolutella citrinellaBF-0440
New compounds, designated voluhemins A (1) and B (2), are isolated from the culture broth of the fungal strainVolutella citrinellaBF-0440 along with structurally related known NK12838 (3). Spectroscopic data, including 1D and 2D NMR, elucidated their structures. Compounds1-3have a common indoline-diterpene core and two additional isoprenyl moieties. Compounds1and3contain a hemiaminal unit, while2isO-methylated1. Their inhibitory activities toward sterolO-acyltransferase (SOAT) 1 and 2 isozymes in SOAT1- and SOAT2-expressing Chinese hamster ovary (CHO) cells show that2selectively inhibits the SOAT2 isozyme.
Synthetic Route of 59-48-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 59-48-3 is helpful to your research.