Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6941-75-9, name is 5-Bromoisoindoline-1,3-dione, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 5-Bromoisoindoline-1,3-dione
General procedure: To a solution of NBP (1.5 mmol, 0.339 g) and DBU (1.5 mmol, 0.218 mL) in MeCN (2.0 mL), ethyl phenylphosphinate 1a (1.0 mmol, 0.154 mL) was added. The reaction mixture was stirred at 0 C for 10 min. After the starting material 1a was consumed as indicated by TLC, the reaction mixture was poured into water and then extracted with CH2Cl2 (3 x 10 mL). The combined organic phase was washed with water (3 x 10 mL), dried over anhydrous MgSO4, filtered and concentrated under reduced pressure. The crude product was purified by flash chromatography (silica gel, petroleum ether: ethyl acetate = 3:1) to give 2a (268 mg, 85%) as a white solid.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 6941-75-9.
Reference:
Article; Li, Yueju; Liang, Fushun; Tetrahedron Letters; vol. 57; 26; (2016); p. 2931 – 2934;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem