Electric Literature of 2913-97-5, These common heterocyclic compound, 2913-97-5, name is N-(2-Oxoethyl)phthalimide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1.46 g of 2- (1,3-dioxoisoindol-2-yl) acetaldehyde, 1.6 g of potassium carbonate,0.64 g of hydroxylamine hydrochloride suspended in ethanol / water mixed solution,Stir overnight at room temperature. The solvent was evaporated under reduced pressure, The residue was diluted with water and extracted with ethyl acetate.The ethyl acetate layer was washed three times with brine and dried over anhydrous magnesium sulfate.The filtrate was concentrated to give 0.75 g of a white solid.
The synthetic route of 2913-97-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Chen, Jianhua; Leng, Ying; Zhu, Junjie; Ning, Mengmeng; (94 pag.)CN103864754; (2016); B;,
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