Related Products of 6780-38-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 6780-38-7 as follows.
Take phthalylglycyl chloride (6.46g, 28.9mmol) a solution in dichloromethane (80 mL), add beta-phenylethylamine (3.55 mL, 28.2 mmol) and triethylamine (7.61 mL, 56.4 mmol). After stirring at room temperature for 1.5 h, add water (30 mL) and extract with dichloromethane (2¡Á40 mL). The organic layer was dried over magnesium sulfate and evaporated. The crude product was purified by crystallization from methanol (50 mL). Yielding a white solid indoleamine (8.20 g, 94%).
According to the analysis of related databases, 6780-38-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NATIONAL HEALTH RESEARCH INSTITUTES; UENG,, SHAU HUA; YEH,, SHIU HWA; CHAO,, PO KUAN; SHIH,, CHUAN; (117 pag.)TW2019/12628; (2019); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem