Adding a certain compound to certain chemical reactions, such as: 64483-69-8, name is 5-Acetylindolin-2-one, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 64483-69-8, COA of Formula: C10H9NO2
General procedure: To a stirred solution of oxindole 7 (1 equiv) in ethanol was added substituted triazole aldehyde 6 (1 equiv) and piperidine (0.01 equiv) and refluxed for 3 h. Completion of the reaction was checked by TLC (n-hexane/EtOAc; 3:7). The product was filtered and was purified using column chromatography (n-hexane/ethyl acetate) to give pure compound [E-8(a-b, d, f-m) and Z-8(a-c, e, i, k-m)] in good yields.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Acetylindolin-2-one, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Nagarsenkar, Atulya; Guntuku, Lalita; Guggilapu, Sravanthi Devi; Danthi Bai; Gannoju, Srinivasulu; Naidu; Bathini, Nagendra Babu; European Journal of Medicinal Chemistry; vol. 124; (2016); p. 782 – 793;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem