611-09-6, name is 5-Nitroindoline-2,3-dione, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. SDS of cas: 611-09-6
General procedure: To a solution of isatins 4a-h (1 mmol) and TiO2 NPs (8 mg, 0.1 mmol, 10 mol%) in water (3 mL), indoles 5a-d (2 mmol) were added and stirred for the indicated time(Table 2) at room temperature. The progress of the reaction was monitored by TLC, however, the same can be inferred by visualizing the disappearance of isatin color and white solid formation. After the consumption of starting material, as indicated by theTLC, the reaction mixture was filtered and the white solid was dried. The obtained solid was then dissolved in ethyl acetate (5 mL) and centrifuged for 1 h at 15000 rpm to separate nanoparticles. Later organic layer was passed through celite pad to remove any particulate impurities from the product and concentrated under reduced pressure. The product was further purified by recrystallization using methanol to give analytically pure 3,3-di(indolyl)indolin-2-ones 6a-r as solid.
The synthetic route of 611-09-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Dwivedi, Kartikey Dhar; Marri, Sameer Reddy; Nandigama, Satish Kumar; Chowhan, L. Raju; Synthetic Communications; vol. 48; 20; (2018); p. 2695 – 2707;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem