Reference of 5332-26-3,Some common heterocyclic compound, 5332-26-3, name is 2-(Bromomethyl)isoindoline-1,3-dione, molecular formula is C9H6BrNO2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Diethyl (aminomethyl)phosphonate was synthesized according to literature procedure (see Kalman et a. Inorg. Chem. 2007, 46, 5260) The compound was isolated as yellow liquid 64% yield (1.082g).?H NMR (300 MHz, CDC13) 4.17-4.08 (m, 4H), 3.01 (d, J 10.3 Hz, 2H), 1.85 (bs, 2H), 1.34 (t, J 7.1 Hz, 6H)
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(Bromomethyl)isoindoline-1,3-dione, its application will become more common.
Reference:
Patent; THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY; TSANTRIZOS, Youla S.; POIRIER, Judes; SEBAG, Michael; BERGHUIS, Albert; PARK, Jaeok; WIM DE SCHUTTER, Joris; WO2014/78957; (2014); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem