1504-06-9, name is 3-Methyloxindole, belongs to indolines-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. SDS of cas: 1504-06-9
A magnetic stirrer was added to the Schlenk tube-sealed reactor, and the 2- oxindole compound of formula II-1 (0.3 mmol) was added, followed by the addition of Cu (OAc) 2 (0.03 mmol) and di-tert-butyl peroxide. (0.6mmol); The reactor was then placed in an oil bath equipped with magnetic stirring, and the reaction was heated and stirred at 120 C for 4 hours. The reaction mixture was completely monitored by TLC. After the completion of reaction, the reaction mixture was concentrated under reduced pressure. The residue was separated by column chromatography (eluent solvent: ethyl acetate / n-hexane) to obtain he title compound formula I-1 , yield 80%.
The synthetic route of 1504-06-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Ningbo University; Bao Wenhui; Wei Wenting; Gao Lehan; Wang Xinye; (11 pag.)CN108129378; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem