Reference of 41663-84-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 41663-84-7, name is 2-Methyl-5-nitroisoindoline-1,3-dione belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
EXAMPLE 3 To a reaction vessel containing dimethylacetamide (25 ml) were added 4-nitro-N-methylphthalimide (0.51 g, 0.00248 mol), biphenyl (0.21 g, 0.00139 mol), sodium hydrogen sulfide (0.14 g, 0.00125 mol) and triethylamine (0.2 ml, 0.0014 mol). The reaction was allowed to proceed at 70 C. for 24 hours. Samples of the reaction mixture were taken and examined by HPLC. A yield of 19.6% 4,4′-bis(N-methylphthalimide)sulfide was indicated. The isolated yield was 18% (0.08 g).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methyl-5-nitroisoindoline-1,3-dione, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; General Electric Company; US4625037; (1986); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem