Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 7477-63-6, name is 7-Chloroisatin, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C8H4ClNO2
In a 100 mL round bottom flask, according to the feed ratio (7-chloroisatin: methanol (1:1.5); 7-chloroisatin: 1,3-diphenylpropanedione (1:1.2))Add 7-chloroisatin 80 mg (0.44 mmol), methanol 21.1 mg (0.66 mmol) and 1,3-diphenylpropanedione 118.7 mg (0.53 mmol), respectively.A catalytic amount (0.1-fold equivalent of 7-chloroisatin) was added to 001¡Á7FC, ferrocene and palladium acetate, and 25 mL of solvent tetrahydrofuran was heated to 90 ¡ã C, and the reaction was heated for 6 hours.The reaction was monitored by thin layer chromatography. After the reaction was completed, the heating was stopped, the condensing device was removed, the mixed system was concentrated under reduced pressure, and purified by column chromatography.The title compound (8) was obtained by drying to give 83.3 mg,yield of 76percent.
According to the analysis of related databases, 7477-63-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shaanxi University of Science and Technology; Liang Chengyuan; Tian Danni; Ding Shunjun; Wang Xuechuan; Dong Hao; Wang Qiang; (15 pag.)CN108395438; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem