Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 65826-95-1, name is 5-Methylindoline, A new synthetic method of this compound is introduced below., Product Details of 65826-95-1
250ml four bottle,In a nitrogen atmosphere,Add 0.01mol 3,6-dibromo-9H-carbazole,0.03 mol of compound 5-methyl 2,3-dihydro-1H-indole,0.03mol of sodium tert-butoxide,1¡Á10-4 mol Pd2(dba)3,1¡Á10-4 mol of tri-tert-butylphosphine,150ml toluene, heated at reflux for 24 hours,Sampling point plate, the reaction is complete, natural cooling, filtration, rotary evaporation of the filtrate, silica gel column to obtain intermediate A10, purity 93.50%, yield 63.60%.
The synthetic route of 65826-95-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jiangsu March Optoelectric Technology Co., Ltd.; Xu Kai; Li Chong; Zhang Xiaoqing; Zhang Zhaochao; (40 pag.)CN107880030; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem