Adding a certain compound to certain chemical reactions, such as: 16800-68-3, name is 1-Acetylindolin-3-one, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 16800-68-3, Quality Control of 1-Acetylindolin-3-one
N-Ethylindole (1.35 g, 10 mmol) and iodine (2.53 g, 10 mmol) were dissolved in ethanol and heated to 80 C. The reaction mixture of 24 After an hour, the extract was extracted with dichloromethane and the organic layers were combined, dried over anhydrous sodium sulfate and recrystallized from dichloromethane / methanol to give N-acetyl-3- (N-ethylindole-3) -indole as a white solid 2.89 g, yield 95%
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Reference:
Patent; Sun Yat-sen University; Weng, Jiang; Lu, Gui; Guo, Jing; (7 pag.)CN105669516; (2016); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem