Reference of 2058-72-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2058-72-2, name is 5-Bromo-1-methylindoline-2,3-dione, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: A mixture of compound 3 (1 mmol) and the appropriate isatinderivative 4a-i (1 mmol) in absolute ethyl alcohol and catalyticamount of glacial acetic acid was heated under reflux for 4 hrs,filtered while hot and the collected solid was washed with ethanol.The crude products 5a-i were re-crystallized from ethanol/DMFmixture (3:1) to furnish the pure title compounds 5a-i in 43-94%yields.
The chemical industry reduces the impact on the environment during synthesis 5-Bromo-1-methylindoline-2,3-dione. I believe this compound will play a more active role in future production and life.
Reference:
Article; Almutairi, Maha S.; Zakaria, Azza S.; Ignasius, P. Primsa; Al-Wabli, Reem I.; Joe, Isaac Hubert; Attia, Mohamed I.; Journal of Molecular Structure; vol. 1153; (2018); p. 333 – 345;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem