Reference of 20780-72-7, The chemical industry reduces the impact on the environment during synthesis 20780-72-7, name is 4-Bromoisatin, I believe this compound will play a more active role in future production and life.
1H-4-Bromoindole-2,3-dione (452.06 mg, 2 mmol), (trimethylsilyl)diazomethane (2 mL of 2M in toluene, 4 mmol), and triethylamine (0.56 mL, 4 mmol) were dissolved in ethanol (10 mL) and placed under argon. It was stirred at room temperature for 18 hours. The resulting suspension was filtered and the solid was collected and dried under vacuum to reveal 5-bromo-3-methoxyquinolin- 2(111)-one as a white solid (267 mg, 53percent); m.p. 286 – 288 ¡ãC; ?H NMR (400MHz, DMSO-d6) 611.97 (s, 1H), 7.31 (dd,J 8Hz, ,J2 Hz, 1H), 7.15-7.09 (m, 2H), 7.02 (s, 1H), 3.73 (s, 3H); ?3C NMR (100 MHz, DMSO-d6) 6 156.9, 150.0, 135.0, 128.0, 125.8, 119.7, 118.6, 114.6, 109.0, 55.7
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromoisatin, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; LAVOIE, Edmond J.; BAUMAN, Joseph David; SAGONG, Hye Yeon; ARNOLD, Eddy; PARHI, Ajit; DAS, Kalyan; VIJAYAN, Suyambu Kesava; PATEL, Disha; WO2014/74926; (2014); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem