Adding a certain compound to certain chemical reactions, such as: 2058-74-4, name is 1-Methylisatin, belongs to indolines-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2058-74-4, Quality Control of 1-Methylisatin
General procedure: Sulfonated-b-cyclodextrin (b-CD-SO3H) (0.1 mmol) was dissolved in water(2 mL) at room temperature by stirring to get the clear solution. Then thereaction was shifted to reflux with addition of isatin (1 mmol) and indole(2 mmol) with constant stirring. The progress of the reaction was monitored byTLC. After completion of reaction, it was cooled to room temperature andfiltered, to get the solid. The crude product was recrystallized from aqueousethanol (60:40) giving pure 3,3-di(indolyl)indolin-2-ones.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methylisatin, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Tayade, Yogesh A.; Patil, Dipak R.; Wagh, Yogesh B.; Jangle, Asha D.; Dalal, Dipak S.; Tetrahedron Letters; vol. 56; 5; (2015); p. 666 – 673;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem