Synthetic Route of 3485-84-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 3485-84-5, name is N-Vinylphthalimide belongs to indolines-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Using N-vinylphthalimide and diphenylphosphine oxide as raw materials, the reaction steps are as follows:Add N-vinylphthalimide (0.069 g, 0.4 mmol) to the reaction flask.Phosphorus phenoxide (0.242 g, 1.2 mmol), trimethylsilyl isothiocyanate (0.157 g, 1.2 mmol), CuBr2 (0.009 g, 0.04 mmol), bipyridyl (0.006 g, 0.04 mmol), manganese acetate (0.322 g, 1.2 mmol) and N-methylpyrrolidone (5 mL), reacted at room temperature;TLC tracks the reaction until it is completely over;The crude product obtained after the reaction is completed is separated by column chromatography (ethyl acetate:dichloromethane = 1:10).The target product was obtained (yield 78%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, N-Vinylphthalimide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Soochow University (Suzhou); Zou Jianping; Tao Zekun; Zhang Peizhi; Li Jianan; (19 pag.)CN107556340; (2018); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem