Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 15861-23-1, name is Indoline-5-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C9H8N2
The 5 – cyano – indoline (1.00 g, 6. 94 mmol) and TEA (2.88 ml, 20.8 mmol) dissolved in DCM (30 ml) in, adding 3 – bromo – benzenesulfonyl chloride (1.95 g, 7.63 mmol) At room temperature overnight and for. Water quenching reaction, divide the DCM layer, for extracting the alternating layer twice twice DCM, the combined DCM layer turns on lathe does after drying, a yellow solid intermediate 1 a (2.26 g, yield: 90%) .
According to the analysis of related databases, 15861-23-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chengdu Xiandao Pharmaceutical Development Co., Ltd.; Li Jin; Wang Wei; Chu Hongzhu; Lv Kaizhi; Liu Lichuan; Nong Yunhong; Chen Wei; (17 pag.)CN110256416; (2019); A;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem