Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 153171-22-3, name is 2-(4-Bromobenzyl)isoindoline-1,3-dione, A new synthetic method of this compound is introduced below., COA of Formula: C15H10BrNO2
To a solution of 2-(4-bromo-benzyl)-isoindole-l ,3-dione (4.1 g, 13.1 mmol, 1.0 eq) in EtOH (50 mL) was added the Nu2 Eta42Omicron (3.3 g, 65.5 mmol, 5.0 eq). The reaction mixture was stirred for 1 h at rt The solvent was evaporated and water was added, and the mixture was extracted with EtOAc. The organic layer was dried over Na2S04 and evaporated to give 4-bromo-benzylamine which was used without purified as a white solid (2.83 g, quant).
The synthetic route of 153171-22-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; LIFESCI PHARMACEUTICALS, INC.; MCDONALD, Andrew; WO2015/103317; (2015); A1;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem