6341-92-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6341-92-0, name is 6-Chloroisatin, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: Microwave Heating: diversity of substituted indoline-2,3-dione 2 (1.0 mmol) was introduced in a 10-mL Initiator reaction vial, diversity of substituent alpha-thiocyanatoethanone 1 (2.0 mmol), EtOH (1.0 mL), and sodium hydroxide (1.0 mmol, 0.040 g) were then successively added. Subsequently, the reaction vial was capped and then pre-stirred for 20 s. The mixture was irradiated (time: 10 min, temperature: 80 C; Absorption Level: High; Fixed Hold Time) until TLC (petroleum ether: acetic ether 3:1) revealed that conversion of the starting material 2 was complete. The reaction mixture was cooled to room temperature. Next, the system was diluted with cold water (20 mL) and neutralized by diluted acidic solution. The solid product was collected by Buechner filtration and was purified by recrystallization from 95% ethanol to afford the pure yellow solid (3a-z)
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Reference:
Article; Wang, Xue; Wu, Qiong; Jiang, Bo; Fan, Wei; Tu, Shu-Jiang; Tetrahedron Letters; vol. 55; 1; (2014); p. 215 – 218;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem