Share a compound : 1-Methylisatin

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2058-74-4, name is 1-Methylisatin, This compound has unique chemical properties. The synthetic route is as follows., 2058-74-4

General procedure: To a mixture of indole-2,3-dione 1a (1.0 mmol) and o-aminothiophenol 2 (1.0 mmol) in distilled water (5.0 mL), was added TBAB (0.0483 g, 15 mol %). This reaction mixture was allowed to stir magnetically at 60 C. Progress of the reaction was monitored by TLC (Pet. ether-ethyl acetate = 4:1) and visualization was accomplished in an iodine chamber. After completion of the reaction, the solid obtained was collected by filtration and washed with warm water. The crude product, so obtained was purified by crystallization with ethanol to afford pure product.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.

Reference:
Article; Jain, Renuka; Sharma, Kanti; Kumar, Deepak; Tetrahedron Letters; vol. 53; 46; (2012); p. 6236 – 6240,5;,
Indoline – Wikipedia,
Indoline | C8H9N – PubChem